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Our CBD formulation contains only pure full Spectrum CBD Oil
No fake Sugar
No Icky green color
7.5mg of cannabidinols CBD per 1 dropperful dose. available in 300mg and 500mg. See labels in photos.
Made in the USA in a sanitary facility. Tested and carefully measured for accuracy of contents in each bottle.
Mild Vanilla Extract Flavor from Pure Vanilla Planiforia. Easy to mix with Honey, your beverage or candy, or just take it plain holding it under the tongue.
Our classic natural CBD oil contains a Full-spectrum of phytocannabinoids without any additional flavors.
300mg is a starter oil recommended for children and adults who have never taken CBD oil.
500mg is an oil for those experienced taking CBD and after using have dosed up to a higher dosage.
Are you looking for a natural way to reduce inflammation?
Inflammation affects pretty much everyone, some chronically. As people become more aware of the side-effects of pharmaceutical drugs and seek more natural solutions, CBD has come into the spotlight… but what does the science say?
First, what is inflammation?
Inflammation is a biological response to something that’s harming our bodies. Although uncomfortable, it’s a sign you’re body is trying to heal itself and without it, you would not be able to recover from infections, wounds or other damage.
So while short-term inflammation can be beneficial, chronic inflammation can cause serious issues including heart disease, diabetes and cancer.
Inflammation and pain
Pain is one of the most common symptoms of inflammation and one that people everywhere are keen to reduce with the use of anti-inflammatory medication such as steroid and non-steroidal (NSAIDs) drugs.
Such medication often carries risk and side-effects, so what about the natural approach?
Reducing inflammation naturally
There are 5 things you can do to reduce or control inflammation naturally:
- Eat an anti-inflammatory diet. Include lots of fruit and vegetables, nuts, olive oil, garlic and spices like ginger and turmeric. Reduce or eliminate red meat and refined sugar and carbs.
- Exercise regularly. Doctors recommend 30-45 minutes of aerobic exercise and 10-25 minutes of resistance training 4 times a week.
- Lose weight. People who are overweight have more inflammation, so practise a healthy eating and exercise regime to keep your weight down.
- Manage stress. Being constantly stressed contributes to inflammation. If it’s a problem for you, look into guided meditations on YouTube or consider yoga.
So what about CBD?
Here at PureKana, we don’t make outlandish claims about our products, our aim is to give you information and the chance to try them for yourself.
Some people believe CBD products help with inflammation, but does it give legitimate relief or is it merely a placebo? Let’s see what the studies say…
- A 2008 study on mice found CBD helped prevent the onset of type 1 diabetes - an inflammatory autoimmune disease that attacks the cells of the pancreas.
- A 2013 study, found that CBD protected against the harmful effects of inflammation in a viral model of multiple sclerosis.
- A 2017 study on mice with osteoarthritis found that acute inflammation of the joints was reduced after two weeks by treating the area directly with CBD.
- This 2018 study showed that CBD binds and desensitizes receptors known to mediate pain inflammation and body temperature.
Although the studies and anecdotal evidence looks promising, we still need many more rigorous trials on humans before we can approve CBD as an effective anti-inflammatory.
What is the endocannabinoid system?
Somewhat confusingly, this internal system is named after cannabis as it’s the plant that led to its discovery.
Back in the ’90s, scientists were trying to understand how THC, the psychoactive compound in marijuana, affected the body. What they found was a complex network of cannabinoid receptors present throughout the body, most notably in the immune system, digestive system, and the brain.
Scientists were intrigued by the discovery as it poses the question, why do we have receptors for cannabinoids if our body doesn’t produce them naturally?
The truth is, the body DOES produce some cannabinoids itself. Two key ones that have been discovered are anandamide (AEA) and 2-arachidonoylglyerol (2-AG).
The two main types of cannabinoid receptors
There are CB1 receptors - mostly found in the central nervous system - and CB2 receptors - found in the peripheral nervous system, especially the immune system.
Endocannabinoids bind to these receptors and the effect depends on which receptor and the type of cannabinoid.
What does the endocannabinoid system do?
The name of the game is homeostasis. Although we’re still researching exactly how it does it, we know its role is to maintain and regulate our body’s processes, including; sleep, mood, appetite, memory, and hormone health.
How does it work?
Your body-produced endocannabinoids or ingested cannabinoids bind to the receptor where action needs to be taken. For example, they might target CB1 receptors in a spinal nerve to relieve pain, or they could target CB2 receptors in the stomach to signal you need food.
CBD and the endocannabinoid system
Although we’re still investigating exactly how CBD interacts with the ECS, research has shown it works differently from other cannabinoids.
Some scientists believe it doesn’t bind to the receptor itself but modifies the receptor’s ability to cling to other cannabinoids. While others claim it prevents endocannabinoids from being broken down, hence making them more effective.
While we know the ECS system exists and plays a key role in regulating our internal process, the details of how it works, especially regarding CBD, are still under debate.
LA PAPPA ORGANICS
CBD DOSAGE GUIDELINES
We get so many emails asking
us about CBD Dosage that
we decided to make this quick informative CBD guide.
Generally speaking, there is no established recommended daily allowance of CBD. There is also no known overdose level. This often leaves consumers completely confused.
1/2 dropperful is a starting point for the average consumer looking for wellness benefits like mental clarity, improved sleep, relief from arthritis and chronic pain, and reduced inflammation.
For mild sleep disorders, 40-160 mg of 300mg CBD Oil (1/4 dropperfuls to ½ dropperfuls) are often used.
For severe sleep disorders 1 to 2 dropperfuls of 500mg per night are often used.
On the other hand, epilepsy and schizophrenia treatment can range from 200-1,200 mg/day ( ½ dropperful to 2 ½ dropperfuls of 500mg) are often used.
Your body weight, your
cannabinoid sensitivity, and desired results should all be considered. The key
though is to experiment.
Start low, go slow! Start low to see if you are sensitive. Slowly dose up by 10-20 drops per day to find your perfect dosage.
Sample Dosage Calculations:
7.5 ( one dropperful) = 7.5 mg OF CBD and 40 mg of Hemp
(approx. 5 ½ dropperfuls) 300mg per day= 41.25 mg CBD and 1500mg of Hemp Oil
( 3 ½ dropperfuls of 500mg CBD per day)= 26.25 mg of CBD and 1500mg of Hemp Oil
( ½ of 500mg CBD per day) = 20mg CBD and 250mg of Hemp Oil
Frequently Asked Questions:
The common side effects of CBD
It’s a fact that everything we put into our bodies could harm us in some way. The good news is that according to most scientific research, the reported side effects of CBD are both rare and mild.
But that doesn’t mean you shouldn’t know about them. So, here are the most common side effects reported by users of CBD.
1 - Drowsiness
Many people take CBD for its relaxing, therapeutic qualities but some have reported it making them feel drowsy or fatigued.
Although uncommon, this could be due to too high a dosage or natural additives in the product - certain terpenes are known to have a sedative effect.
2 - Stomach upset
The digestive system is a finely balanced machine and some things we ingest - especially new things - can cause upset. Again it’s uncommon, but some people have reported nausea and diarrhoea after using CBD products.
Because it can be difficult knowing how much to take at first, these issues are most likely due to incorrect dosing.
3 - Changes in appetite and weight
Although marijuana is often claimed to increase appetite (the ‘munchies’), some CBD users have reported a reduced appetite and weight loss.
A 2017 study found that weight loss was a common side effect when used to treat seizures in people, as well as animal subjects.
4 - Headaches
There are few reports of people having headaches after using CBD oil but as like other side effects, this is likely due to taking too large of a dose.
If you do experience a headache, alter your dose accordingly.
5 - Lower blood pressure
Some users have reported lower blood pressure after using CBD. Again, this could be due to taking too high a dose, but some studies have shown a link between CBD and lower blood pressure.
Do you take any prescription medication? If so, read on...
Piles of research have deemed CBD as safe for most uses with very few, albeit mild, side effects - in the World Health Organization’s (WHO) critical review of CBD, it states that ‘CBD is generally well tolerated with a good safety profile’.
CBD does have the potential to interact with certain medications and to ensure that you don’t have any adverse reactions, we’re going to explore more.
Please note: If you take any prescription medication and you’re concerned about CBD’s possible interaction with it, your first port of call should be your doctor. Don’t take what we say as medical advice.
Why might CBD interact with my meds?
Any medication you take has to be broken down by the body - or metabolized. This largely occurs in the liver with the help of a group of enzymes called cytochromes P450 or CYP450.
Some medications or supplements can affect CYP450 and the way other drugs are metabolized and processed by the body. This is known as a drug interaction.
Research has shown that a particular enzyme within the CYP450 group, CYP3A4, is responsible for metabolizing cannabinoids like CBD, which in turn, inhibits CYP3A4.
CYP3A4 not only deals with cannabinoids, but it also has to metabolize other drugs you might be taking (about 60% off prescribed medications). And, if it’s been inhibited by CBD, it can’t process these meds as effectively, meaning you may have more in your system than you should.
Knowing which drugs CBD might interact with: A rule of thumb
While we wait for more research into CBD’s effects on CYP3A4, there is a rule of thumb that can tell you whether or not there could be an interaction with your meds.
Look for the grapefruit warning on your medication.
Many drugs warn against consuming grapefruit, grapefruit juice, pomelos, and similar fruits while taking them as they can lead to a higher concentration of the drug in the body. This is because grapefruit contains chemicals that inhibit CYP3A4 - just like CBD.
So, if your medication has this warning, it would be best to avoid taking CBD before talking to your doctor.
Does CBD impair driving?
Some of us like to have our daily dose in the morning before we take on the day, or a little later, when we need an afternoon pick-me-up. But, considering CBD can help us to relax, it leads many to question, “Should I be driving right now?”
Until now, very little research has been done on this topic.
But a Dutch study, published recently in the Journal of the American Medical Association, has shed light on CBD’s effects on driving as well as its infamous cousin THC.
The study, led by the Lambert Initiative for Cannabinoid Therapeutics at the University of Sydney but conducted at the Maastricht University in the Netherlands, tested people in a ‘real-life’ driving situation - on a highway rather than a simulator.
The 26 male and female subjects were selected based on their cannabis usage - less than twice a week in the last year but more than 10 times in their life. After vaping different mixes of CBD and THC, the participants then went for a 100km (62 miles) drive on a public highway under controlled conditions both 40 minutes and 4 hours after they vaped.
The mixes were as follows:
- 13.75 milligrams of THC dominant mix
- 13.75 mg of THC/CBD even mix
- 13.75 mg of CBD dominant mix
- A placebo
Lane weaving, average speeds and range of speeds were measured, and after the drive, the participants self-rated their driving confidence and had their memory, decision-making, and thinking skills evaluated by the researchers.
The study concluded that driving was impaired after the THC dominant mix and the THC/CBD mix was vaped, but only when the subjects drove 40 minutes after taking - after 4 hours, any impairment was gone.
Most importantly for you and I, vaping the CBD dominant mix did not impair driving.
Critics of the study have said that the doses might be lower than what an average CBD user takes, so driving impairment can’t be completely ruled out at higher doses. However, the leaders of the study have promised to set up a driving simulator to test a wider range of CBD doses in the near future.
The study suggests that using CBD products with trace amounts of THC should not impair driving. But, of course, you are your best judge. If you feel tired, drowsy, or anything else that might affect your driving, just don’t get behind the wheel.
In the CBD market, you can’t always be sure what you’re getting, and there’s always a chance that your product contains something different than what’s on the label.
But here at LaPappa Organics, we have our USA-made CBD products independently tested to verify their contents - that means you’ll never get more THC than you bargained for.
Does CBD Help Veterans?
We have over 17 million veterans in the US and nearly half of all males aged over 75 once served our great country.
Unfortunately, many of our honored veterans are living with chronic health issues like pain, PTSD, anxiety, and depression. A study, released by the US Department of Veteran Affairs (VA) in 2016, claims that an average of 20 veterans commits suicide every day.
Why are so many veterans turning to CBD?
Well, we can only speak for our customers, many of whom are US veterans.
CBD oil and other products offer therapeutic benefits that have the potential to improve the quality of life of many ex-and-current servicepeople.
As CBD is federally legal and doesn’t get you high, it’s much easier to get access to than medical marijuana for example. What’s more, in order for our CBD products to be more affordable to veterans, we offer a Veteran’s Discount Program that allows servicemen and women to get 25% off our entire range of premium CBD products for life.
What are the issues that Veterans commonly face?
PTSD (Post-Traumatic Stress Disorder)
Between 10-20% of veterans experience some form of PTSD - that’s 3 to 6 times higher than the average for civilians.
Although more is needed, the research into PTSD and CBD looks promising, take this review, for example, which indicates that many military veterans with PTSD are using cannabis and derivative products (CBD) to effectively control symptoms.
The VA is also researching how CBD could be used as an add-on to prolonged exposure therapy to speed up the recovery from PTSD.
Among servicemen and women, anxiety disorders have increased by 327% since 2000 and often go hand in hand with PTSD.
One of the most common reasons that people are interested in CBD is to help them relax and better deal with life’s struggles - and nobody knows these like our nation’s veterans.
Insomnia is one of the main symptoms of PTSD and as sleep can be impacted by anxiety and pain, veterans are often seeking ways to improve their sleep.
The therapeutic benefits of CBD may help ease stress and help veterans get better sleep, which in turn, will have a knock-on effect in other areas of their life.
Not only do veterans experience more pain than civilians, but they’re also prone to more severe pain - especially in young and middle-aged veterans.
Many are prescribed opioids for pain relief - but these carry a high amount of risk. The US has scarily high rates of opioid addiction with more than 130 Americans dying each day from overdoses.
There have been studies that suggest that CBD could be as effective as opioids in dealing with pain and so could be an excellent choice for veterans.
What is the biphasic effect of CBD?
Maybe you’ve noticed this yourself - in small doses, CBD is a mild stimulant, but more than a certain amount and it becomes a mild sedative.
This explains why a common ‘side effect’ to CBD is drowsiness - normally down to having taken too much.
How can I benefit from CBD’s biphasic effect?
Of course, we all process CBD in different ways and dosage is largely a case of trial and error - certainly in the beginning. But by keeping the biphasic effect in mind, it can help you choose a suitable dose.
For example, if you take CBD twice daily, you might want to take less in the morning than you do at night. That way you’ll benefit from the stimulating effect when you need it - and not be yawning in your morning meeting!
As there is no official guidance, choosing the perfect dosage of CBD can be tricky. But, by knowing the compound’s biphasic nature, we have a clearer idea of how much CBD we need for our goals.
And although it may make you drowsy, CBD is safe even in large doses.
Want something a little stronger?
Our USA-made CBD oils come in a range of concentrations - from 300mg up to a high-strength 500mg
Here are 4 untruths about CBD some people still believe:
Myth #1: CBD is marijuana:
People often associate cannabis with marijuana when in fact it’s just one form of the plant. Yes, marijuana contains CBD but it’s bred for its high THC content (the compound that gets you high). The CBD is our products is sourced from lab derived and measured hemp with accurate testing for containing No THC.
Myth #2: CBD gets you high
Because of its low THC content (less than 0.2% to be exact), CBD is 100% non-psychoactive, meaning it won’t get you high, stoned, baked - or whatever the kids are calling it.
Myth #3 CBD is illegal in the USA
Hemp-derived CBD with less than 0.3% THC is legal at the federal level with the passage of the Farm Bill in 2018.
Myth #4 CBD and hemp oil are the same things.
Although made from the same plant, CBD oil comes from the cannabidiol-rich flowers, leaves, and stalks while hemp oil is made from the seeds. Hemp oil contains little to no CBD but possesses different health benefits.